Spatial omics and multiplexed imaging are rapidly advancing technologies that have transformed our ability to explore cancer biology. By providing high-resolution, spatially resolved molecular data, these methods enable researchers to study the intricate interactions within tumor microenvironments. Such insights are crucial for understanding tumor heterogeneity, immune responses, and the mechanisms driving cancer progression. As these techniques continue to evolve, they hold the promise of uncovering new therapeutic targets and improving personalized treatment strategies for cancer patients.