The journey of the human body begins in infancy, often marked by flawless perfection. However, as time elapses and individuals grow, the passage of time become evident on their skin. From minor mosquito bites to major surgical incisions or burns, wounds of varying sizes leave enduring marks on the body. While some wounds heal swiftly, leaving no visible trace, others persist over the years,...

The current diagnostic criteria for SSD place a greater emphasis on patient behavior assessment and frequently involve patient self-assessment, which is very subjective and not helpful for early diagnosis or efficacy evaluation. The scientific reliability of SSD diagnosis will be significantly increased if optimal biomarkers for SSD can be discovered. To ensure high purity of mRNA during...

In the past few decades, both pharmaceutical companies and academia have spent much financial resources and energy to improve the practicability and accuracy of in vitro screening technology that can test the biological activity and physicochemical properties of compounds. However, the study of potential drug candidates in animal models remains disposable. FDA, NMPA, and other regulatory...

The hallmark of rheumatoid arthritis (RA) is erosive arthritis, an autoimmune disease that ultimately results in joint deformities and functional loss. It can also be complicated by pulmonary disease, cardiovascular disease, malignant tumors, and depression. The etiology of RA remains unclear. However, infections have been suggested as environmental triggers in as many as 20% of patients. Due...